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Tubes for obtaining fibrin PRF, 10ml

Vacuum glass tube for PRF. No anticoagulants, 0.6% siliconization. Creates dense fibrin scaffold for surgical applications, dentistry, wound healing.

€110

Class IIa medical device

Not a laboratory tube. Certified for therapeutic use (ISO 13485). The cost difference compared to laboratory tubes is less than 2% of the procedure price. Why does this matter?

Volume:

10 ml

Purpose:

PRF solid

Anticoagulant:

None

1

Medical devices are intended for use by qualified healthcare professionals in accordance with the manufacturer's instructions. The information on the website is for informational purposes only and does not replace medical consultation. More details

Certified. Products have undergone the conformity assessment in accordance with the Technical Regulation on Medical Devices (CMU Resolution No. 753). ISO 13485:2016 quality management system. View certificates

Natural fibrin formation in medical glass

Medical glass provides natural coagulation activation allowing to obtain dense PRF clot or membrane for surgical use. Without any chemical anticoagulants — only natural blood properties.

Key characteristics

Final product Cell-rich fibrin
Tube material Medical glass
Anticoagulant Немає
Separation gel No
Blood draw volume 10 ml
PRF 10 ml Tube

How it works

PRF (Platelet-Rich Fibrin) — concentrate of autologous platelets, leukocytes and growth factors captured in dense fibrin matrix. Unlike PRP where blood remains liquid thanks to anticoagulant, PRF forms through controlled blood coagulation.

PRF technology principle

Fibrin matrix provides slow, prolonged growth factor release for 7-14 days, unlike one-time release when using liquid PRP.

Medical glass role

Glass is natural coagulation activator — this is key feature of PRF tubes. Controlled fibrin matrix formation ensures uniform cell distribution in clot.

Why without anticoagulant?

Anticoagulant blocks blood coagulation — exactly what needed for PRF formation. Absence of anticoagulant is mandatory condition.

Dense structured PRF clot with high mechanical strength
Possibility of membrane formation for surgical use
Sticky bone — combination with bone substitutes
Natural coagulation activation without chemicals
Dense 3D fibrin matrix formation
Creation of biologically active scaffold for regeneration

What you will get

Final product characteristics

Dense yellow-white clot (after compression — a membrane), three-dimensional fibrin matrix, approximately 2–3 cm long.

Biological activity

PRF matrix contains and gradually releases:

Cellular composition: Platelets + leukocytes (neutrophils, monocytes)
Mechanical properties: Elastic, strong, suitable for surgery
PDGF — cell proliferation stimulation
TGF-beta — collagen synthesis, osteogenesis
VEGF — angiogenesis, vascularization
IGF-1 — cell proliferation
EGF — epithelium regeneration
BMP — osteoinduction
Shape Application
PRF clot Bone defect filling, sockets
PRF membrane Wound covering, GBR, GTR
PRF crumb (plug) Mixing with bone material
Sticky bone Augmentation, sinus lift

Usage time

PRF clot should be used within 30 minutes after centrifugation while fibrin matrix maintains optimal consistency and biological activity.

Period Activity
Day 1-3 Initial release, regeneration launch
Day 4-7 Peak growth factor release
Day 8-14 Gradual decrease, tissue integration

Advantage over PRP

Prolonged release provides sustained regeneration stimulation for 10-14 days, unlike one-time release with PRP injection.

Clinical application

Glass PRF tube intended for surgical interventions where biologically active material needed for filling or covering.

Direction Indications
Dentistry / Implantology Socket preservation after extraction, implant osseointegration acceleration, peri-implantitis treatment, sinus lift
Maxillofacial surgery Alveolar ridge augmentation, GBR (guided bone regeneration), GTR (guided tissue regeneration), oroantral communication closure
Periodontology Gum recession treatment, furcation defect closure, periodontal tissue regeneration
Orthopedics / Traumatology Fracture union stimulation, non-union treatment, cartilage regeneration
Surgery Wound healing acceleration, chronic ulcer treatment, donor site covering
Plastic surgery Graft support, post-operative wound healing improvement

Best suited for

Surgical interventions where biologically active material needed for filling or covering; bone regeneration and augmentation; cases where mechanical strength important and surgical manipulation possibility; combination with bone substitutes (sticky bone).

Why choose this tube

Medical glass

Activates coagulation for dense PRF clot formation with high mechanical strength.

Controlled fibrin formation

Optimal process of quality fibrin matrix formation with uniform cell distribution.

Without anticoagulant

Natural coagulation with complete biological activity and growth factor preservation.

Product versatility

Clot, membrane, crumb or sticky bone — different forms for different clinical needs.

Prolonged release

Growth factors work 10-14 days, providing sustained regeneration stimulation.

Mechanical strength

PRF withstands surgical manipulation, suture fixation and mechanical load.

Centrifugation protocol recommendations

Protocol Result
L-PRF (Choukroun) Standard speed, 12 min — dense clot, rich in platelets
A-PRF Reduced speed, 14 min — softer clot, more leukocytes
A-PRF+ Minimum speed, 8 min — optimized cell distribution

Choose protocol depending on clinical situation and centrifuge manufacturer recommendations.

Recommended usage protocol

Protocol compliance ensures obtaining quality PRF clot with maximum therapeutic potential.

1

Preparation

Check package integrity and expiration date. Prepare PRF box for membrane formation (if needed). Prepare necessary equipment: blood collection needle, holder, centrifuge.

2

Blood draw

Perform venipuncture using standard technique. Wait for complete tube filling (10 ml).

3

Centrifugation

Install tube in centrifuge vertically. Balance rotor. Choose protocol depending on clinical situation: standard L-PRF or softer A-PRF for more leukocytes. Don't exceed recommended parameters — excessive force damages cells.

4

Obtaining PRF

Carefully remove tube. Visually assess separation: upper layer — acellular plasma (PPP), middle layer — PRF clot (yellow-white), lower layer — erythrocytes (dark red). Using forceps remove PRF clot. Separate clot from erythrocyte layer (leave 1-2 mm red part — most cells there).

5

Membrane formation (if needed)

Place PRF clot in PRF box. Gently compress with lid to remove excess fluid. Obtained membrane ready to use. Collected fluid (exudate) can be used for bone material moistening.

6

Application

Use PRF within 30 minutes. For sticky bone — mix crushed PRF with bone graft. Fix membrane with sutures or under flap.

Critically important

Critical: immediately place tube in centrifuge — coagulation begins immediately after blood contact with glass!

Why do therapeutic tubes cost more than laboratory tubes?

MM Medic tubes are class IIa medical devices certified for therapeutic use. Laboratory tubes (IVD) are intended exclusively for testing and disposal, not for introduction into the human body.

Contents

Safe anticoagulants (citrate, heparinate) or no additives (PRF)—formulated for therapeutic use. Laboratory tubes contain EDTA, which irreversibly destroys platelets.

Material

Medical borosilicate glass or special medical-grade PET—selected for the specific therapeutic protocol. Laboratory tubes are not designed for contact between their contents and the patient's tissues.

Certification

ISO 13485:2016, safety class IIa, gamma sterilization, individual sterile packaging. Laboratory tubes carry only an IVD marking.

Note

The cost difference compared to laboratory tubes is 50–80 UAH—less than 2% of the procedure cost (2,500–5,000 UAH). Using uncertified tubes for injections violates the law and puts the patient's health at risk. Learn more in the FAQ

Important warnings

Single use only. Re-sterilization prohibited.

For autologous use only — PRF used exclusively for patient from whose blood it was obtained.
Time critical! Place tube in centrifuge immediately after blood collection (within 1-2 minutes).
Use PRF within 30 minutes after centrifugation.
Prohibited to use with damaged packaging, presence of cracks or after expiration date.

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